The Genetics of Speech and Language Impairments</tile> <meta http-equiv="Content-Type" content="text/html; charset=utf-8"> <meta http-equiv="description" content="The Genetics of Speech and Language Impairments"> <meta http-equiv="keywords" content="The,Genetics,of,Speech,and,Language,Impairments"> </head> <body> <table width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="10" height="39"> </td> <td width="99%" height="39"> <table width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="16%"><a href="http://inttranews.inttra.net"><img src="http://inttranews.inttra.net/images/inttranews_grey_2.jpg" width="192" height="37" border="0"></a></td> <td width="50%" valign="middle"> <p><font face="Arial, Helvetica, sans-serif" size="2"><b><font color="#CCCCCC" face="Verdana, Arial, Helvetica, sans-serif" size="1">KNOW.<br> HOW.</font></b></font> </p> </td> <td width="34%" align="right" valign="top"><font face="Verdana, Arial, Helvetica, sans-serif" size="1" color="#666666">06-11-2008</font></td> </tr> </table> </td> </tr> <tr> <td width="10"> </td> <td width="99%" > </td> </tr> <tr> <td width="10"> </td> <td width="99%" > <table width="100%" border="0" cellspacing="0" cellpadding="0"> <tr> <td width="100%"><font face="Verdana, Arial, Helvetica, sans-serif" size="2"> <b>The Genetics of Speech and Language Impairments</b></font> </td> </tr> <tr> <td width="100%"> </td> </tr> <tr> <td width="100%"> <img src="http://inttranews.inttra.net/img_news/img_PtHdwssjTEctDhN9SrNb_0.jpg" align="left" vspace="5" hspace="5" ><font face="Verdana, Arial, Helvetica, sans-serif" size="2">Massachusetts, USA (New England Journal of Medicine): The FOXP2 protein has many transcription targets in the brain. In this issue of the Journal, Vernes et al.report that FOXP2 down-regulates the expression of CNTNAP2, a gene that encodes a neurexin protein. Using scores on tests of nonsense-word repetition for children with specific language impairment as an endophenotype, they further show that particular CNTNAP2 variants are associated with specific language impairment. <br> <br>For more information, please visit: <br><a href="http://content.nejm.org/cgi/content/full/NEJMe0807813 " target="blank">content.nejm.org/cgi/content/full/NEJMe0807813 </a> <br></font></td> </tr> </table> </td></tr> </table> <script type="text/javascript"></script> <script type="text/javascript" src="<http://pagead2.googlesyndication.com/pagead/show